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SASA Calculator

Measure protein surface exposure by structure, chain, and residue.

Overview

Calculate solvent-accessible surface area for a protein structure. Reports whole-structure, chain, and residue SASA, along with buried surface area and the fraction of exposed residues that are hydrophobic.

Run SASA Calculator on Neurosnap

The SASA Calculator online webserver allows anybody with a Neurosnap account to run and access SASA Calculator, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.

SASA Calculator service preview

Features

  • Measures total solvent-accessible surface area in square angstroms.
  • Reports per-chain and per-residue SASA in the full structure.
  • Compares isolated-chain and assembled-chain exposure to estimate buried surface area.
  • Reports the fraction of exposed protein residues that are hydrophobic.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

Statistic Value
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API Request

Access SASA Calculator using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Citations

Please cite the original work when using SASA Calculator in publications or research outputs.

Amani, Keaun, and Danial Gharaie Amirabadi. 2024. Neurosnap SDK Package. Software. https://github.com/NeurosnapInc/neurosnap.

Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/

Set up your run

Configure SASA Calculator

Choose your inputs and settings, then review the estimated credits before submitting.

Use a note to recognize this job later. It does not affect the results.

Inputs & configuration

Loading inputs and options... validating knobs, tuning dials, and staging your experiment.

Ready to submit your job?

Review your configuration, then confirm the estimated credit cost before you run the job.

Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

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