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TSignal Signal Peptide Prediction

Predict signal-peptide types, residue labels, and cleavage sites.

Overview

TSignal predicts five N-terminal signal-peptide types and candidate cleavage sites using a transformer model. Inspect residue labels and download predicted mature protein sequences.

Run TSignal Signal Peptide Prediction on Neurosnap

The TSignal Signal Peptide Prediction online webserver allows anybody with a Neurosnap account to run and access TSignal Signal Peptide Prediction, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.

TSignal Signal Peptide Prediction service preview

Features

  • Distinguish Sec/SPase I, Sec/SPase II, Tat/SPase I, Tat/SPase II, and Sec/SPase IV signal peptides.
  • Inspect predicted labels and conditional confidence for the first 70 residues.
  • Locate candidate cleavage sites and flag non-contiguous signal predictions.
  • Download prediction CSVs and candidate mature protein sequences in FASTA format.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access TSignal Signal Peptide Prediction using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Citations

Please cite the original work when using TSignal Signal Peptide Prediction in publications or research outputs.

Dumitrescu A et al. TSignal: A transformer model for signal peptide prediction. bioRxiv (2022). https://doi.org/10.1101/2022.06.02.493958.

Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/

Set up your run

Configure TSignal Signal Peptide Prediction

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Inputs & configuration

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