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ProTrek

Search Swiss-Prot proteins, structures, and annotations with sequence, structure, or text queries.

Overview

Search UniProtKB/Swiss-Prot using a protein sequence, single-chain structure, or functional description. ProTrek 650M retrieves related proteins, structural representations, or annotations from the complete published Swiss-Prot database.

Run ProTrek on Neurosnap

The ProTrek online webserver allows anybody with a Neurosnap account to run and access ProTrek, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.

ProTrek service preview

Features

  • Search from amino acid sequences, single-chain structures, or natural-language descriptions.
  • Retrieve proteins, structural representations, or any of 56 Swiss-Prot annotation categories.
  • Inspect ranked matching scores and download CSV results.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access ProTrek using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Citations

Please cite the original work when using ProTrek in publications or research outputs.

A trimodal protein language model enables advanced protein searches. Nature Biotechnology (2025). doi:10.1038/s41587-025-02836-0.

Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/

Set up your run

Configure ProTrek

Choose your inputs and settings, then review the estimated credits before submitting.

Use a note to recognize this job later. It does not affect the results.

Inputs & configuration

Loading inputs and options... validating knobs, tuning dials, and staging your experiment.

Ready to submit your job?

Review your configuration, then confirm the estimated credit cost before you run the job.

Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

Estimated Credits: calculating...

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