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PSSM Profile Comparison

Align two reusable profiles using symmetric probability overlap rather than an HMM method. Scores are in bits and have no calibrated E-values.

Overview

Align two reusable profiles using symmetric probability overlap rather than an HMM method. Scores are in bits and have no calibrated E-values.

Run PSSM Profile Comparison on Neurosnap

The PSSM Profile Comparison online webserver allows anybody with a Neurosnap account to run and access PSSM Profile Comparison, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.

PSSM Profile Comparison service preview

Features

  • Local or global probability-overlap alignment with affine gaps.
  • Explicit common background when input profile backgrounds differ.
  • Gapped consensus alignment and original coordinates for both profiles.
  • Download overlap scores and the actual comparison background.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access PSSM Profile Comparison using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Citations

Please cite the original work when using PSSM Profile Comparison in publications or research outputs.

Amani, Keaun, and Danial Gharaie Amirabadi. 2024. Neurosnap SDK Package. Software. https://github.com/NeurosnapInc/neurosnap.

Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/

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Configure PSSM Profile Comparison

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Inputs & configuration

Loading inputs and options... validating knobs, tuning dials, and staging your experiment.

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