Use NeuroFold2

Official Neurosnap webserver for accessing NeuroFold2 online.

Overview

NeuroFold2 leverages a state-of-the-art hybrid engine, combining generative AI with physics and evolutionary principles. This allows for the simultaneous, high-fidelity optimization of multiple enzyme properties, delivering novel candidates with unparalleled performance.

Neurosnap Overview

The NeuroFold2 online webserver allows anybody with a Neurosnap account to run and access NeuroFold2, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.

Features

  • Powered by our proprietary NeuroFold2 model.
  • Simultaneously optimizes for thermostability, pH stability, solubility, and catalytic reaction rate.
  • Uses a hybrid architecture of AI, physics-based simulations, and evolutionary signals.
  • Unlocks innovative enzyme designs with significant mutations that lead to enhanced performance.
  • De-risks R&D by computationally screening thousands of variants to identify top candidates for wet-lab validation.
  • Specialized for active site engineering with full awareness of ligand and substrate interactions.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access NeuroFold2 using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Job Note

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Inputs & Configuration

Loading inputs and options... validating knobs, tuning dials, and staging your experiment.

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