Isoelectric Point Calculator
Sequence-only pI/pKa prediction (IPC 1/2).
Overview
Predict isoelectric point (pI) or pKa values from amino-acid sequences using IPC classic scales (IPC1) or IPC2 SVR/deep models.
Run Isoelectric Point Calculator on Neurosnap
The Isoelectric Point Calculator online webserver allows anybody with a Neurosnap account to run and access Isoelectric Point Calculator, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.
Features
- Classic IPC1 scales (Bjellqvist, EMBOSS, ProMoST, etc.) with optional ALL aggregation.
- IPC2 SVR models for protein and peptide pI.
- IPC2 deep conv2d peptide pI.
- IPC2 pKa SVR (per-residue predictions).
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
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API Request
Access Isoelectric Point Calculator using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
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Citations
Please cite the original work when using Isoelectric Point Calculator in publications or research outputs.
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Kozlowski LP. IPC - Isoelectric Point Calculator. Biology Direct 2016;11:55. |
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Kozlowski LP. IPC 2.0 - prediction of isoelectric point and pKa dissociation constants. NAR 2021;49(W1):W285–W292. |
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Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/ |