EvoEF2
Protein stability and binding energy analysis using EvoEF2.
Overview
EvoEF2 is an energy function for detailed protein structure analysis. It computes the overall stability of a given protein structure and calculates specific binding energies between defined protein chains or groups of chains within a protein complex. EvoEF2 is recognized for its accuracy and computational speed in these energy calculations.
Run EvoEF2 on Neurosnap
The EvoEF2 online webserver allows anybody with a Neurosnap account to run and access EvoEF2, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.
Features
- Protein stability assessment.
- Offers detailed analysis of binding interactions, determining energy values for associations between different proteins or specific inter-chain contacts within a complex.
- Powered by the EvoEF2 physical energy function, known for its computational efficiency and accuracy in evaluating protein energies.
- Powered by Neurosnap's Python implementation of EvoEF2, with comparable accuracy and support for a wider range of atom types and molecular systems.
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
| Statistic | Value |
|---|---|
| Credit Usage Rate | loading... |
| Estimated Total Cost | loading... |
| Runtime Mean | loading... |
| Runtime Median | loading... |
| Runtime Standard Deviation | loading... |
| Runtime 90th Percentile | loading... |
| Runtime Longest | loading... |
API Request
Access EvoEF2 using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
Similar Tools
Explore tools with similar features, categories, and use cases.
Citations
Please cite the original work when using EvoEF2 in publications or research outputs.
|
Huang X, Pearce R, Zhang Y. EvoEF2: accurate and fast energy function for computational protein design. Bioinformatics. 2020 Feb 15;36(4):1135-42. |
|
Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/ |