Use CodonTransformer

Official Neurosnap webserver for accessing CodonTransformer online.

Overview

A multispecies codon optimization model that leverages attention-based deep learning to generate host-specific DNA sequences with natural-like codon usage profiles. Trained on over 1 million DNA-protein pairs from 164 organisms, it enables context-aware, high-fidelity predictions tailored to protein expression needs.

Neurosnap Overview

The CodonTransformer online webserver allows anybody with a Neurosnap account to run and access CodonTransformer, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.

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Features

  • Multispecies support spanning 164 organisms across all kingdoms of life.
  • Context-aware predictions using transformer-based attention mechanisms.
  • Customizable optimization with control over stochasticity, sequence matching, and output diversity.
  • Supports batch inference and automatically handles ambiguous amino acids.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access CodonTransformer using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

Job Note

Provide a name or description for your job to help you organize and track its results. This input is solely for organizational purposes and does not impact the outcome of the job.

Configuration & Options

Service Inputs

The input amino acid sequence that corresponds to the protein you want to optimize the codons of.

Select the host you want to optimize protein expression in.

Specifies how many output sequences to generate. A value of 1 results in deterministic generation, while values greater than 1 enable stochastic sampling of sequences

Ready to submit your job?

Once you're done just hit the submit button below and let us do the rest.

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