ANARCI
ANARCI provides standardized numbering and chain classification for antibody and TCR domains.
Overview
ANARCI is a sequence analysis tool for numbering antibody and TCR variable domains. It provides standardized numbering, chain classification (H, K/L, A, B, G, D), and optional germline gene assignment, helping researchers interpret immune receptor repertoires. Built to be fast and scalable, it processes single sequences or large datasets efficiently.
Run ANARCI on Neurosnap
The ANARCI online webserver allows anybody with a Neurosnap account to run and access ANARCI, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.
Features
- Standardized numbering of antibody and TCR sequences (IMGT, Kabat, Chothia, Martin, Wolfguy, Aho).
- Chain classification for heavy, light, and TCR domains.
- Optional germline gene assignment.
- Batch processing support for large-scale immune repertoire analysis.
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
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API Request
Access ANARCI using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
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Citations
Please cite the original work when using ANARCI in publications or research outputs.
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James Dunbar, Charlotte M. Deane, ANARCI: antigen receptor numbering and receptor classification, Bioinformatics, Volume 32, Issue 2, January 2016, Pages 298–300, https://doi.org/10.1093/bioinformatics/btv552 |
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Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/ |