Use ABACUS-R Sequence Design

Official Neurosnap webserver for accessing ABACUS-R Sequence Design online.

Overview

ABACUS-R designs sequences by predicting sidechains of a central residue based on its local three-dimensional environment. ABACUS-R predicts one high fidelity sequence that is then folded and returned.

Neurosnap Overview

The ABACUS-R Sequence Design online webserver allows anybody with a Neurosnap account to run and access ABACUS-R Sequence Design, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.

View Paper

Features

  • Uses an encoder-decoder to predict sequences using local 3-dimensional structural environments.
  • Produces self-consistent sequences to a target backbone.
  • Backed by X-Ray Crystallography experiments, showing state-of-the-art performance.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access ABACUS-R Sequence Design using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

Job Note

Provide a name or description for your job to help you organize and track its results. This input is solely for organizational purposes and does not impact the outcome of the job.

Configuration & Options

Service Inputs

The input protein structure to predict a new sequence for. Accepts pdb and mmcif structure files. The input protein structure cannot exceed 1200 residues and must be monomeric.

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