Use QEPPI

Overview

QEPPI is a specialized index for early-stage screening of compounds targeting protein-protein interactions (PPIs). It extends the concept of drug-likeness quantification beyond traditional methods like QED, offering a continuous, adjustable metric tailored for PPI-targeting drug discovery. Built from experimental PPI data rather than FDA-approved drugs, QEPPI is ideal for identifying seed compounds that may evolve into PPI inhibitors or stabilizers, supporting both virtual screening and generative modeling applications.

Neurosnap Overview

The QEPPI online webserver allows anybody with a Neurosnap account to run and access QEPPI, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.