Use CatPred

Official Neurosnap webserver for accessing CatPred online.

Overview

CatPred is a deep learning framework for predicting in vitro enzyme kinetic parameters, including turnover numbers (kcat), Michaelis constants (Km), and inhibition constants (Ki). It addresses key challenges such as the lack of standardized datasets, performance evaluation on enzyme sequences that are dissimilar to those used during training, and model uncertainty quantification.

Neurosnap Overview

The CatPred online webserver allows anybody with a Neurosnap account to run and access CatPred, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.

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Features

  • Predicts turnover numbers (kcat), Michaelis constants (Km), and inhibition constants (Ki).
  • Provides query-specific uncertainty estimates.
  • Uses pretrained protein language models (PLM).
  • Performs competitively with existing methods while offering reliable uncertainty quantification.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access CatPred using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Job Note

Provide a name or description for your job to help you organize and track its results. This input is solely for organizational purposes and does not impact the outcome of the job.

Configuration & Options

Service Inputs

An amino acid sequence for the enzyme.

Input small molecules (substrates) to include in prediction. All inputs are converted to SMILES format.

The kinetic parameter to predict.

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