Use NeuroBind

Official Neurosnap webserver for accessing NeuroBind online.

Overview

The most advanced tool for designing high-affinity binders like antibodies, nanobodies, scFvs, and peptides against any target. NeuroBind combines AI, physics, and evolutionary principles for best-in-class performance.

Neurosnap Overview

The NeuroBind online webserver allows anybody with a Neurosnap account to run and access NeuroBind, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.

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Features

  • Supports the design of antibodies, nanobodies, scFvs, and peptides against arbitrary protein or complex targets.
  • Automatically performs in silico affinity maturation, achieving predicted affinities in the -15 to -20 kcal/mol range.
  • Allows programmable design for properties such as high solubility, low immunogenicity, and enhanced thermal/solvent stability.
  • Employs a hybrid AI framework combining deep learning with evolutionary constraints and physics-based simulations.
  • Outperforms pure ML-based approaches in both predicted binding affinity and developability.
  • Produces diverse candidate binders that adhere to biologically realistic structural and functional constraints.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access NeuroBind using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

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Video Tutorial

The following youtube video describes how to use NeuroBind using Neurosnap's online webserver. If you have any questions or want to suggest improvements for future tutorials please contact us here.

Job Note

Provide a name or description for your job to help you organize and track its results. This input is solely for organizational purposes and does not impact the outcome of the job.

Inputs & Configuration

Loading inputs and options... validating knobs, tuning dials, and staging your experiment.

Ready to submit your job?

Review your configuration, then confirm the estimated credit cost before you run the job.

Note that credit estimates are not guaranteed and runtime can vary depending on inputs and settings.

Estimated Credits: calculating...

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