Use MUSCLE v5 MSA Generation
Official Neurosnap webserver for accessing MUSCLE v5 MSA Generation online.
Overview
MUSCLE v5 is a novel multiple sequence alignment algorithm that generates an ensemble of high-accuracy MSAs with diverse biases. It achieves this by perturbing a hidden Markov model (HMM) and permuting the guide tree used in the progressive alignment.
Neurosnap Overview
The MUSCLE v5 MSA Generation online webserver allows anybody with a Neurosnap account to run and access MUSCLE v5 MSA Generation, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.
Features
- Generates high-quality multiple sequence alignments for biological sequences, with demonstrated accuracy improvements over popular tools like Clustal-Omega and MAFFT.
- Constructs an ensemble of MSA replicates by introducing controlled variations in the HMM parameters and guide tree, enabling assessment of alignment uncertainty and bias.
- Designed to scale to alignments of tens of thousands of sequences using a divide-and-conquer strategy.
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
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API Request
Access MUSCLE v5 MSA Generation using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
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