Use Humatch
Official Neurosnap webserver for accessing Humatch online.
Overview
Humatch is a fast, gene-specific tool designed to jointly humanize antibody heavy and light chains. Leveraging lightweight convolutional neural networks (CNNs), Humatch classifies human antibody sequences with near-perfect accuracy and guides the humanization process by aligning sequences with specific human germline V-genes. It ensures optimal VH/VL pairing to maintain stability and expression while reducing immunogenicity risks. Additionally, Humatch provides robust classification of antibody sequences, distinguishing between human and non-human origins with high precision.
Neurosnap Overview
The Humatch online webserver allows anybody with a Neurosnap account to run and access Humatch, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong Terms of Use and Privacy Policy.
Features
- Jointly humanizes antibody heavy (VH) and light (VL) chains for better pairing and stability.
- Ensures alignment with specific human germline V-genes, avoiding hybrid gene designs.
- Reduces immunogenicity risks while maintaining expression and binding efficiency.
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
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API Request
Access Humatch using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
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Job Note
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Inputs & Configuration
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