Use EvoProtGrad Protein Evolution

Official Neurosnap webserver for accessing EvoProtGrad Protein Evolution online.

Overview

Identify residues to mutate via a gradient-based discrete Markov chain Monte Carlo sampler.

Neurosnap Overview

The EvoProtGrad Protein Evolution online webserver allows anybody with a Neurosnap account to run and access EvoProtGrad Protein Evolution, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.

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Features

  • Perform directed evolution on a protein sequence with gradient-based discrete Markov chain Monte Carlo (MCMC).
  • Allows focused mutation experiments on protein sequences with known function.
  • Identifies residues to mutate via model gradients taken with respect to the user input.

Statistics

Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.

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API Request

Access EvoProtGrad Protein Evolution using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.

Job Note

Provide a name or description for your job to help you organize and track its results. This input is solely for organizational purposes and does not impact the outcome of the job.

Configuration & Options

Service Inputs

The input protein / amino acid sequence to perform directed evolution on.

Select the expert to create the product of experts distribution during your experiment.

The number of evolution steps to perform on your target protein. The more steps the longer the job runtime.

You may adjust the max mutations/variant from 1 to 20.

Ready to submit your job?

Once you're done just hit the submit button below and let us do the rest.

To submit a job please login or register an account.