DiffAb Antibody Design
Design Antibodies for a target Antigen using the Antigen structure. DiffAb leverages a probabalistic diffusion model.
Overview
DiffAb generates Antibodies for specific Antigen structures using a first-of-its-kind deep learning model. DiffAb emphasizes design using the structure and sequences of complimentary-determining regions (CDR).
Run DiffAb Antibody Design on Neurosnap
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Features
- Design Antigen-specific Antibodies from Antigen structures.
- Utilizes a genartive diffusion based model for Antibody design.
- DiffAb emphasizes design using the structure and sequences of complimentary-determining regions (CDR).
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
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API Request
Access DiffAb Antibody Design using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
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Citations
Please cite the original work when using DiffAb Antibody Design in publications or research outputs.
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Shitong L. et al., Antigen-Specific Antibody Design and Optimization with Diffusion-Based Generative Models for Protein Structures, https://www.openreview.net, 31 October 2022, https://openreview.net/forum?id=jSorGn2Tjg. |
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Neurosnap Inc. (2022). Neurosnap: An online platform for computational biology and chemistry. Available at: https://neurosnap.ai/ |