Use ProteinMPNN
Official Neurosnap webserver for accessing ProteinMPNN online.
Overview
ProteinMPNN is a powerful inverse folding model that is capable of not only predicting the amino acids of a protein structure, but also certain chains, and complexes. Additionally, ProteinMPNN can be used as a way to create functional homologs / mutants of existing proteins by inverse folding their structures and sampling the sequence space.
Neurosnap Overview
The ProteinMPNN online webserver allows anybody with a Neurosnap account to run and access ProteinMPNN, no downloads required. Information submitted through this webserver is kept confidential and never sold to third parties as detailed by our strong terms of service and privacy policy.
View PaperFeatures
- Predecessor to LigandMPNN. Note this service has been largely replaced by LigandMPNN and should no longer be used.
- Utilizes the faster & more feature rich ColabDesign implementation of ProteinMPNN.
- Supports SolubleMPNN.
- Allows you to specify fixed chains and positions.
- Allows you to inverse fold any protein or complex of proteins.
- Supports homo-oligomers.
- Supports different sampling techniques to better explore the protein landscape.
- Includes per sequence metrics such as an overall score and sequence recovery.
- Includes amino acid probabilities by position.
- Includes sampling temperature adjusted amino acid probabilities by position.
Statistics
Neurosnap periodically calculates runtime statistics based on job execution data. These estimates provide a general guideline for how long your job may take, but actual runtimes can vary significantly depending on factors like input size or settings used.
Statistic | Value |
---|---|
Credit Usage Rate | loading... |
Estimated Total Cost | loading... |
Runtime Mean | loading... |
Runtime Median | loading... |
Runtime Standard Deviation | loading... |
Runtime 90th Percentile | loading... |
Runtime Longest | loading... |
API Request
Access ProteinMPNN using the Neurosnap API by sending a request using any programming language with HTTP support. To safely generate an API key, visit the API tab of your overview page.
Video Tutorial
The following youtube video describes how to use ProteinMPNN using Neurosnap's online webserver. If you have any questions or want to suggest improvements for future tutorials please contact us here.
Job Note
Provide a name or description for your job to help you organize and track its results. This input is solely for organizational purposes and does not impact the outcome of the job.
Configuration & Options
Ready to submit your job?
Once you're done just hit the submit button below and let us do the rest.
To submit a job please login or register an account.